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Algorithms and Methods in Structural Bioinformatics -

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2022-09-02
101,63 € 169,38 €

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The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support thi ... Täielik kirjeldus

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Kirjeldus

The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support this field, a rich set of methods and algorithms are available, addressing a variety of important problems such as protein-protein interactions, the effect of mutations on protein structure and function, and protein structure determination. Despite recent advancements in the field, in particular in protein folding with the development of AlphaFold, many problems still remain unsolved.

In this book we focus on a number of topics in Structural Bioinformatics: Cryo-EM structural detection, protein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding.

Lisateave

Kirjastaja Springer Nature Switzerland
Series Computational Biology
Väljalaskeaasta 2022
Kaanetüüp Kõvakaaneline
EAN 9783031059131
Kirjuta oma arvustus
Te vaatate: Algorithms and Methods in Structural Bioinformatics
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101,63 € 169,38 €