The researchers have been coordinating research on multi-key enabling technologies that bring together efforts involving advanced materials and biology during the last few years. These breakthroughs are enabling for the development of novel biomimetic systems that are addressing social concerns and have a great potential for innovation and growth.The use of biocompatible and biomechanically active materials that can be designed to reproduce bone compatible and biomimetic scaffolds that can adapt themselves in mutating physiological conditions is presented in the present book.