After having her travel papers stolen to research in India, Dr. Persephone 'Perse' Teixeira succumbs to living in her sister's basement and working in retail. Just as she's about ready to hit rock bottom, Perse is offered an opportunity to teach anthropology and history at Chesapeake Bay University. Perse is thrilled; now her only worry is managing her anxiety. However, that changes once she meets a science professor, Dr. Stefanie 'Stef' Blake.

Stef is cute, quick-witted, and a touch neurotic. She's also very interested in dating Perse. When Perse declines her romantic advances because it is imperative that she focuses on her new job, Stef explains she has a relationship system that consists of six levels, which will ensure perfect compatibility before marriage. It's casual, slow, and, really, what are the odds of getting to level six?

Perse is amused, yet intrigued by Stef's analytical approach, and agrees to go out with her. But logic only goes so far and when feelings start to grow, Perse must contend with her anxiety issues, because history has taught her nothing good comes out of falling in love.

Are Perse and Stef compatible enough to get through the levels? Will Perse's past cause her to run before they can find out? Or did Stef create the perfect system for happily ever after?