Modelling Proteasome Dynamics in a Bayesian Framework - Sabine Stübler
-40% koodiga BOOKS
Saadetis 10-16 tööpäeva jooksul
30-päevane tagastamisõigus
Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in in vitro experiments. The computational model, which describes the hydrolysis of short fluorogenic peptides by the 20S protea ... Täielik kirjeldus
Võib-olla meeldib sulle ka
TOP
The Myth of Normal: Trauma, Illness, and Healing in a Toxic Culture
-40% koodiga BOOKS
Meie tarnija laos
TOP
No Bad Parts: Healing Trauma and Restoring Wholeness with the Internal Family Systems Model
-40% koodiga BOOKS
Meie tarnija laos
TOP
The Checklist Manifesto: How to Get Things Right
-40% koodiga BOOKS
Meie tarnija laos
TOP
Harrison's Principles of Internal Medicine (Vol.1 & Vol.2)
Stephen Hauser, Joseph Loscalzo, Steven Holland, Dan Longo, J. Larry Jameson, Dennis Kasper, Carol Langford, Anthony Fauci
-40% koodiga BOOKS
Meie tarnija laos
TOP
The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma
-40% koodiga BOOKS
Meie tarnija laos
TOP
Maybe You Should Talk to Someone: a therapist, her thearapist, and our lives revealed
-40% koodiga BOOKS
Meie tarnija laos
TOP
How Not To Die: Discover the foods scientifically proven to prevent and reverse disease
-40% koodiga BOOKS
Meie tarnija laos
TOP
Lifespan: Why We Age - and Why We Don't Have To
-40% koodiga BOOKS
Meie tarnija laos
TOP
Vademecum Metabolicum: Diagnosis and Treatment of Inborn Errors of Metabolism Forword by William L. Nyhan, San Diego, USA
Johannes Zschocke, Georg F. Hoffmann
-40% koodiga BOOKS
Meie tarnija laos
TOP
ROAR: How to Match Your Food and Fitness to Your Unique Female Physiology for Optimum Performance, Great Health, and a Strong, Lean Body for Life
-40% koodiga BOOKS
Meie tarnija laos
TOP
Cellular and Molecular Immunology
Sarah Henrickson, Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai
-40% koodiga BOOKS
Meie tarnija laos
TOP
McGee's Evidence-Based Physical Diagnosis
-40% koodiga BOOKS
Meie tarnija laos
TOP
Physics, Pharmacology and Physiology for Anaesthetists: Key Concepts for the FRCA
Matthew E. Cross, Emma V. E. Plunkett
-40% koodiga BOOKS
Meie tarnija laos
TOP
Pocket Guide to Teaching for Clinical Instructors
-40% koodiga BOOKS
Meie tarnija laos
TOP
Oxford Handbook of Critical Care
Andrew Webb, Mervyn Singer, Alice Carter
-40% koodiga BOOKS
Meie tarnija laos
TOP
The Wills Eye Manual: Print + eBook with Multimedia: Office and Emergency Room Diagnosis and Treatment of Eye Disease
-40% koodiga BOOKS
Meie tarnija laos
TOP
Vaccinated - dead: Histopathological findings following COVID-19 vaccination
-40% koodiga BOOKS
Meie tarnija laos
TOP
Steal Like an Artist: 10 Things Nobody Told You About Being Creative
-40% koodiga BOOKS
Meie tarnija laos
Kirjeldus
Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in in vitro experiments. The computational model, which describes the hydrolysis of short fluorogenic peptides by the 20S proteasome, is calibrated to experimental data from different proteasome isoforms using an approximate Bayesian computation approach. The dynamics of proteasome inhibitors are included into the model in order to demonstrate how to modulate the inhibitor’s transport parameters for strong or isoform-specific inhibition.
Lisateave
| Autor | Sabine Stübler |
|---|---|
| Kirjastaja | Springer Fachmedien Wiesbaden |
| Väljalaskeaasta | 2017 |
| Kaanetüüp | Pehme kaanega |
| EAN | 9783658201661 |