Within a state, the political regime, the public institutions, politicians, the police, the army, lose credibility and thus the legitimacy they should have because of the development of drug trafficking; drug trafficking can compete and surpass the sovereignty of the state. The formation of a Narco-State is a threat to the national security and sociopolitical stability of any country. Drug trafficking has relevance as a social phenomenon, it influences all aspects of society, in the economic, political, cultural and international context.This short research paper discusses how this business develops, how it unfolds. This text took as reference the States in which drug trafficking has developed rampantly, such as Mexico, Colombia and Bolivia. It looks at what drug trafficking is in politics, what is organized crime, how drug trafficking influences the culture, and the economic power that this industry obtains, economic power that is used for political purposes, going so far as to corrupt the different authorities of the state and it's institutions. Narco-State is a term that is intimately linked to the concepts of drug trafficking, money laundering, terrorism, white trafficking, prostitution, corruption and many ills that have been generated in recent decades, thanks to the presence of the international mafia and the so-called drug cartels.