THE SERIES The 10 volumes in this series record a fifty year history of neuropsychopharmacology related by 213 pioneer clinical, academic, industrial and basic scientists in videotaped interviews, conducted by 66 colleagues between 1994 and 2008. These volumes include a preface by the series editor placing its contents in an historical context and linking each volume to the next. Each volume is dedicated to a former President of the ACNP and edited by a distinguished historian or Fellow of the College who provides an introduction to its themes and a biography of each scientist’s career. The series provides insights into a half century of discovery and innovation with its rewards and disappointments, progress and setbacks, including future expectations and hopes for the field as a whole and the ACNP as an organization. IN THIS VOLUME In Volume 1, 22 pioneers reflect on their contributions to the “Starting Up” of neuropsychopharmacology in the 1950s, using behavioral methodology to detect differences in the pharmacological profile of newly introduced psychotropic drugs. In Volume 2, “Neurophysiology,” the emphasis shifts to the detection of the action of drugs on the functional activity of the brain. Volume 2 is divided into two parts. In Part One (Electrophysiology), 15 interviewees reflect on their contributions to the detection of the effect of drugs on the electrical activity of the brain and in Part Two (Brain Imaging), 5 interviewees talk about their contributions to the study of cerebral blood flow and brain metabolism Dedicated to the memory of Jonathan O. Cole, President, 1966, Volume 2 is edited by Max Fink, a leading American psychiatrist who was instrumental in the introduction of “pharmaco-EEG,” using digital computer analysis of the electroencephalogram to identify active psychotherapeutic drugs following the model of the association of EEG and behavior in man.