Based on the author's lecture notes and research, this well-illustrated and comprehensive text is one of the first to provide an introduction to image registration with particular emphasis on numerical methods in medical imaging. Ideal for researchers in industry and academia, it is also a suitable study guide for graduate mathematicians, computer scientists, engineers, medical physicists and radiologists. Providing a systematic and general framework for image registration, the book not only presents state-of-the-art concepts but also summarizes and classifies the numerous techniques to be found in the literature.