The continuously increasing need for human organ donors has led to the tremendous advancements in the area of organ bioengineering. A bioartificial organ is a man-made device with the purpose of replacing the native organ. The complex process of organ manufacturing involves several key considerations regarding the replication of the anatomical and physiological organization and microarchitecture of native organs. In this process, the choice of cells, biomaterials, and microfabrication and organ maturation techniques plays a crucial role in the final outcome of the bioengineered structure. This book offers a state of the art of the recent advancements in developing bioartificial brain, heart, lung, kidney, liver, bone, tendon, ligament, cartilage, and skin.