Compaction of powder constituents―both active ingredient and excipients―is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of Pharmaceutical Powder Compaction Technology guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel thro ...Täielik kirjeldus
Compaction of powder constituents―both active ingredient and excipients―is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of Pharmaceutical Powder Compaction Technology guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application.This unique reference covers:The physical structure of pharmaceutical compactsBonding phenomena that occur during powder compactionCompression mechanisms of pharmaceutical particlesTheories and basic principles of powder compactionNew topics include:Compaction data analysis techniquesThe migration of powder constituents into commercial manufactureInstrumentation for compactionCompaction functionality testing, which is likely to become a USP requirementDesign space for compactionMetrics required for scalability in tablet compressionInteractive compaction and preformulation database for commonly used excipients