It is said that the canal will be the greatest feat of engineering in history. But first, it must be built. For Francisco, a local fisherman who resents the foreign powers clamoring for a slice of his country, nothing is more upsetting than the decision of his son, Omar, to work as a digger in the excavation zone. But for Omar, whose upbringing was quiet and lonely, this job offers a chance to finally find connection. Ada Bunting is a bold sixteen-year-old from Barbados who arrives in Panama as a stowaway alongside thousands of other West Indians seeking work. Alone and with no resources, she is determined to find a job that will earn enough money for her ailing sister's surgery. When she sees a young man, Omar, who has collapsed after a grueling shift, she is the only one who rushes to his aid. John Oswald has dedicated his life to scientific research and has journeyed to Panama in single-minded pursuit of one goal: eliminating malaria. But now, his wife, Marian, has fallen ill herself, and when he witnesses Ada's bravery and compassion, he hires her on the spot as a caregiver. This fateful decision sets in motion a sweeping tale of ambition, loyalty, and sacrifice.